Mast Cell Tumors
Mast Cell Tumors - Caring Hands Animal Hospital
Gastrointestinal stromal tumors GISTs are the most common mesenchymal neoplasms of the gastrointestinal tract. GISTs arise in the smooth muscle pacemaker interstitial cell of Cajal , or similar cells. GIST was introduced as a diagnostic term in Histopathologists were unable to specifically distinguish between types we now know to be dissimilar molecularly. Subsequently, CD34 , and later CD were identified as markers that could distinguish the various types. Due to the change in definition, clinical pathways of care before the year are largely uninformative in the current era. GISTs may present with trouble swallowing , gastrointestinal bleeding , or metastases mainly in the liver.
Mast cells and canine mast cell tumours. A review
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